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Studies designed to provide insight into clinical practice in the real world are known as pragmatic trials. They are typically described as a focus on the practical aspects of designing a study, including the recruitment and consent process, as well as adherence and the use routinely available equipment.

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A pragmatic study that involves a variety investigators and includes participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity is necessary for pragmatic trials to be able to prove their validity and 프라그마틱 공식홈페이지 also reduces the chance of bias in the results. However too much heterogeneity could cause issues with the design of the trial.

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Pragmatic trials are designed to replicate real-life settings and achieve maximum external validity. They are typically commissioned by practitioners and policy makers to inform their decision making. They can also be a great way to identify the cause-effect relationship between an intervention and its results. However, they should not be used in lieu for explanatory studies.

The pragmatism idea is controversial and there are concerns about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 made an distinction between explanation-based studies, which support the physiological hypothesis or clinical hypothesis, as well as pragmatic trials, which inform the practice and policy decision-making. They also suggested a framework dubbed PRECIS for 프라그마틱 환수율 pragmatic trials.2 This tool tried to define the elements of a pragmatic study, including recruitment, 프라그마틱 정품인증 design, implementation of the intervention, and follow-up.

The number of pragmatic trials is increasing. A recent Medline search using the terms pragmatic and 프라그마틱 무료스핀 naturalistic, restricted to controlled trials randomized to control (RCTs) resulted in 34 articles, shown in red in Figure 2. This indicates that the health sciences community is becoming more aware of the importance of pragmatism. It is important to keep in mind, however, that the majority of studies were conducted in primary-care settings.